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The structural composition of JWH-210 features a naphthalene ring attached to an indole core having a pentyl facet chain. This molecular composition is accountable for its selective receptor binding and strong effects within the cannabinoid program.
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It can be changed at R1 using a pentyl chain. The indole Main is substituted at R3 using a carbonyl group which can be also connected to a naphthalene moiety.